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KMID : 0356920090570020249
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Korean Journal of Anesthesiology
2009 Volume.57 No. 2 p.249 ~ p.253
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Was a hypertensive crisis in a patient with pheochromocytoma caused by rocuronium - A case report -
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Jeong Cheol-Won
Bae Hong-Beom
Lee Hyung-Gon
Kim Woong-Mo
Shin Seung-Heon
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Abstract
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Pheochromocytoma is an uncommon tumor that originates in the adrenal medulla or in other paraganglia of the sympathetic nervous system. If a hypertensive crisis occurs during general anesthesia in incidental or untreated pheochromocytoma, it is a life-threatening event with a mortality rate of about 80%. Anesthetic drugs such as pancuronium, atracurium, and metoclopromide can exacerbate the potentially lethal cardiovascular effects of catecholamines. We report a case of a patient with pheochromocytoma who display abrupt increases in systolic arterial pressure and plasma norepinephrine following rocuronium administration. This case indicates the possible involvement of elevated sympathetic nervous system to a catecholamine crisis triggered by rocuronium in pheochromocytoma.
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KEYWORD
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Catecholamine, Hypertensive crisis, Pheochoromocytoma, Rocuronium
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